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As a support chitosan presents interesting characteristics
2020-04-29

As a support, chitosan presents interesting characteristics that reinforce its great potential for enzyme immobilization [18,19]. Firstly, it is produced from renewable natural sources in addition to being biodegradable and water insoluble [20,21]. Also, the main peculiarity in the chitosan structu
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br Materials and methods br Results br Discussion Our
2020-04-29

Materials and methods Results Discussion Our results based on the Y2H analysis between the U-box-motif region of E3s and the UBC domain of E2s showed that, among 40 rice E2s, 11 E2s accounted for 70% of the interactions with 17 ARM-U-box E3 Ub-ligases (Fig. 2, Fig. 3). These 11 E2s belong t
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Consistent with previous simulations on
2020-04-29

Consistent with previous simulations on the DFG-Asp-out/-in interconversion of Abl kinase, we only observe the DFG flip with protonated Asp747 (Shan et al., 2009). We showed previously that the pKa for the DFG-Asp in Abl is elevated at 6.5. Further “constant pH” simulations whereby protonation event
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Within the cluster of North African populations
2020-04-29

Within the cluster of North African populations the Sousse population sample is somewhat different from the other six populations. One has to analyze more in depth the reasons of this isolation that has been shown by other genetic studies (Fadhlaoui-Zid et al., 2015). It seems that the particular ge
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Exon encodes a section of the extracellular ligand binding d
2020-04-29

Exon 3 encodes a section of the extracellular ligand-binding domain and two variants in the 5′ region were first identified in Drosophila melanogaster (Semenov and Pak, 1999). These variants were initially termed modules 1 and 2 and correspond to exons 3a and 3b, respectively. To date, exon 3 altern
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A recent report has shown that C elegans homozygous
2020-04-29

A recent report has shown that C. elegans homozygous for a point mutation within the HORMA domain of HTP-1 (M127K), which disrupts its association with chromosome axes, displayed an extended zone of PLK-2 localization to PCs in response to asynapsis (Silva et al., 2014), which, as we show here, is a
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Notochord is a transient structure differentiating at early
2020-04-28

Notochord is a transient structure differentiating at early stage during embryogenesis that is at the origin of vertebral bodies in all vertebrates. In zebrafish, it is composed of vacuolated Oseltamivir phosphate surrounded by a unique ECM structure improperly called notochordal BM. As in chicken
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pepstatin Protein degradation via UPP involves
2020-04-28

Protein degradation via UPP involves two steps. One step is the conjugation of multiple ubiquitin to a substrate. The other step is the degradation of tagged protein by the downstream 26S proteasome complex. Protein ubiquitination is the E1–E2–E3 enzymatic cascade (Hershko & Ciechanover, 1998). E1-a
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Because flavonoids are widely considered to contribute to he
2020-04-28

Because flavonoids are widely considered to contribute to health benefits in humans, including anti-inflammatory, antibacterial, antiviral, anticancer, antiplatelet properties, and free radical scavenging capacity (Xiao et al., 2011), efforts have frequently been made to increase their bioavailabili
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These contrasting results observed with intra
2020-04-28

These contrasting results observed with intra-BNST combined injections of NOC-9 and CP 376395 on freezing (in the novel arena) versus anxiety-related behavior (in the EPM) suggest that CRF neurotransmission within this forebrain limbic site could be mainly involved in the modulation of more subtle a
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The proposed FDIR technique is presented in
2020-04-28

The proposed FDIR technique is presented in the following format: Section 2 contains a survey of typical orbits of interest with regard to the Apremilast environment found in them, which is contrasted with a LEO orbit. Additionally, how the requirements for the satellite system can be estimated is p
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fasudil In frame exon skipping of COL A has been
2020-04-28

In frame exon 41 skipping of COL6A3 has been suspected to be responsible for isolated dystonia in several human kindreds without muscular defects [94]. In order to validate their hypothesis, the authors used zebrafish to selectively knock down several exons in col6a3 and found a negative impact on m
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Materials and methods br Results br Discussion
2020-04-28

Materials and methods Results Discussion Microbial production of trans-4Hyp, an added-value amino H-Lys(Ac)-OH.HCl for pharmaceuticals, offers significant advantages over conventional chemical extraction in economic and environmental aspects. However the low titer and productivity with the
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Limitations of the current study in addition
2020-04-28

Limitations of the current study, in addition to the ones highlighted above, are its retrospective nature, the potential biased selection of patients requiring bronchoscopy for the etiological diagnosis of pneumonia, the lack of normalization of CMV DNA loads in BAL fluids to cellular DNA content (a
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Next our exploration shifted to modifications at the lateral
2020-04-28

Next, our exploration shifted to modifications at the lateral chain of the benzoquinone nucleus (SAR 2). Considering that the CK2 inhibitory activity is favoured by the presence of the -Ph-4-NO2 (SAR 1), the subsequent analogues were investigated with this moiety retained. The influence of the side
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